Cannabis Dispensary Lancaster

4.6
StarStarStarStarHalf Star
(756 Reviews)

Catalyst Lancaster is a licensed recreational and medical cannabis dispensary at 42020 4th St E, just east of Sierra Highway near the Columbia Way intersection on the southern edge of town.

The store opens 9am to 9:30pm every day and holds 4.6 stars across 756 Google reviews. Flower, pre-rolls, vapes, concentrates, edibles, topicals, and tinctures are stocked with tax already included, and online orders wait at the counter.

Location marker

Directions & Location — Cannabis Lancaster

Facility information

About this Facility

  • License type: Recreational (21+) and medicinal (18+ with a valid physician's recommendation)

  • State license: C10-0001458-LIC

  • Parking: Free parking with store security on site while you shop

  • Payment: Debit card and cash. No credit cards. ATM inside the store

  • Accessibility: Wheelchair accessible

  • Ordering: Order online for in-store pickup. No delivery, no shipping, no curbside

  • First-time discount: 10% off your first purchase

  • Pets: Service animals only

About This Location

Catalyst on 4th Street East

The Antelope Valley sits north of the San Gabriel Mountains, separated from the Los Angeles Basin below. Lancaster is Catalyst's only store in the valley, with the next location more than 35 miles away in Van Nuys.

Flower, vapes, pre-rolls, concentrates, edibles, topicals, and tinctures are all under one roof at the southern end of town.

Weed for the People is how we price. Tax is already included, so what you see is what you pay, and a Cat 4 sticker means that product cleared our own pesticide panel, wider than the state requires.

Read our full story here.

The Neighborhood

The store sits at the southern edge of Lancaster, east of Sierra Highway near Columbia Way (Avenue M).

Air Force Plant 42, which shares a runway with Palmdale Regional Airport, is 2.6 miles southeast. The Antelope Valley Mall is 3.3 miles southwest, over the Palmdale line.

North of here, the Lancaster Metrolink station is 3.6 miles and The BLVD, the downtown strip, about 3.8. Antelope Valley College sits 4.3 miles northwest.

Further out, Quartz Hill is five and a half miles west, the Antelope Valley Fairgrounds six miles northwest, and the Poppy Reserve sixteen and a half miles out toward the western edge of the valley.

Past the city line, this store serves Palmdale, Quartz Hill, Rosamond, Acton, Lake Los Angeles, Sun Village, Littlerock, and Antelope Acres.

Local Deals

Check out the latest deals and discounts available at Catalyst Cannabis Lancaster.

View Deals at Cannabis Lancaster

Deals rotate at Lancaster the same way they do chain-wide. Tax is already included, so the percentage you read is the percentage you save.

Running chain-wide right now, availability varies by location:

Deal Discount
Catalyst house brands (Cat 4 and MJuice) 20% off
Beard Bros Pharms 40% off
Connected and Alien Labs 30% off
BLEM 30% off
Cannabiotix 25% off

First-time customers get 10% off their first purchase. See every current deal or join the Catalyst Rewards Club.

Reviews section

Customer Reviews

Catalyst Lancaster holds 4.6 stars across 756 Google reviews. Here's what people say after they've been in.

"Shout out to the folks working here! I have had nothing but good experiences here at Catalyst! They have a great selection, amazing deals, and the people working here have been nothing but extremely kind and helpful. If you come on a Friday or Saturday be prepared for a little wait, but I promise it's worth it!" - Ellie. Google Review, February 2026.

"This place is much bigger than anything I have seen in San Fernando Valley. They are Very well stocked. The customer service is by far the Best I have ever enjoyed at a dispensary. All of the employees seem to be incredibly knowledgeable about the products. Coco stands out to me.

She was compassionate, patient and answered every one of my questions. When I leave , I know I always have the best products for my personal needs. I highly recommend this place." - Stephanie. Google Review, March 2026.

"Brittany is the best she has the best welcoming energy and such a beautiful smile that matches her energy as well she helped me try some new blunts today from sluggers I would highkey recommend and told me more daily deals! AMAZING SERVICE !" - Joseph Razo. Google Review, June 2026.

What We Carry

Six categories on the 4th Street floor. Here's what's in each and what to ask for.

Cannabis Flower

Flower sells by weight at 4th Street, from a single gram upwards.

Blue Zushimi, Black Mamba, Royal OG, and Skywalker OG rotate through the wall here, with Astronauts, Coastal Sun, and Smoken Promises among the cultivators.

Browse the flower menu.

Pre-Rolls

Two things share this shelf. Finished pre-rolls come as singles and multi-packs, ready to smoke; empty cones are the paper on its own, for packing with flower you buy separately.

Among the finished ones, infused versions have concentrate worked into the flower and are typically more potent than standard rolls. Cizi, California Love, and Astronauts cover the range, and a Cat 4 house single runs $5, or $4 on the house-brand hookup.

See the pre-roll menu.

Vapes and Cartridges

Vapes outsell every other category Catalyst stocks. Before flavor, settle the format: a standalone cartridge needs a battery you already own, while an All-in-One arrives charged with one built in.

Plugplay, Halfpipe, Blem, and our own Cat 4 line are all in the Lancaster case. Keep whichever you buy upright and out of a hot car, because desert heat thins the oil and thin oil is what leaks past the seals.

See the vape menu.

Concentrates

Concentrates are the strongest thing on the 4th Street floor, made by isolating the plant's trichomes and pressing them together. Budder, shatter, and crumble name the texture, not the grade.

You'll need a rig or a dab pen for any of it, so mention it at the counter if you don't own either. Astronauts, Wvy, and the Catalyst line cover most of the case.

See the concentrate menu.

Edibles

Edibles are the smoke-free option on the Lancaster shelf, and the number worth reading is milligrams per piece, not per pack.

Onset runs slow, up to two hours, which is long enough that people assume nothing is happening and take a second. Drops, Wyld, Punch Edibles, and Whoa are stocked here.

See the edibles menu.

Topicals and Tinctures

Not everything in here is meant to get you high. The topicals shelf holds balms, lotions, and patches for the skin, and non-intoxicating options are common, though it varies by product.

Tinctures come in a dropper bottle, marked so you can measure before taking a dose under the tongue or in a drink. Papa & Barkley and Buddies are the names here.

Browse topicals and tinctures.

Neighborhoods and Landmarks We Serve

Catalyst Lancaster sits at the southern edge of town near Columbia Way, which puts both Antelope Valley cities within a short drive.

  • Air Force Plant 42: About 2.6 miles southeast

  • Antelope Valley Mall, Palmdale: About 3.3 miles southwest

  • Lancaster Metrolink station: About 3.6 miles north

  • The BLVD, downtown Lancaster: About 3.8 miles north

  • Antelope Valley College: About 4.3 miles northwest

  • Quartz Hill: About 5.5 miles west

  • Antelope Valley Fairgrounds: About 6 miles northwest

  • Apollo Community Regional Park: About 8 miles northwest

  • Antelope Valley California Poppy Reserve: About 16.5 miles northwest

The store also serves Rosamond, Acton, Lake Los Angeles, Sun Village, Littlerock, and Antelope Acres.

Buying Cannabis Legally in California

Medical cannabis has been legal here since 1996. Recreational use came in with Proposition 64, and the first licensed shops opened in 2018.

At the 4th Street counter, the rules run like this:

  • Anyone 21 or over buys recreational cannabis on a government-issued photo ID. Medicinal patients from 18 need a physician's recommendation, and a county-issued MMIC is accepted in its place though never required.

  • A day's limit is an ounce of flower, 28.5 grams, alongside 8 grams of concentrate. Medicinal patients can go to 8 ounces, and higher still where the recommendation says so.

  • Nobody has to be a California resident to buy recreational cannabis, and visitors face the same limits as locals. Medicinal purchases need a recommendation from a physician licensed in California.

  • Consumption is limited to private property. Streets, sidewalks, parks, and desert trailheads are all off limits, and cannabis can't be taken across state lines.

The rest is covered in our guides to California cannabis laws and how to purchase weed in California.

FAQ section

Dispensary in Cannabis Lancaster FAQs

We can't wait to welcome you to our dispensary in Cannabis Lancaster. As you plan your visit, here are a few helpful things to keep in mind.

42020 4th St E, Lancaster, CA 93535, just east of Sierra Highway near the Columbia Way intersection.

Nine in the morning until half past nine at night, seven days a week at 4th Street, holidays included unless we post otherwise.

Yes. Free parking at 4th Street, with store security keeping an eye on the lot while you shop.

Yes. The 4th Street store is wheelchair accessible.

Not for recreational purchases. Adults 21+ just need a valid government-issued photo ID. Medicinal patients 18+ need a valid physician's recommendation; a county-issued MMIC works too, but it isn't required.

Both. C10-0001458-LIC covers adult-use and medicinal retail.

An ounce a day of flower, which is 28.5 grams, plus 8 grams of concentrate. Medicinal patients can go up to 8 ounces, or more if their recommendation specifies it.

Debit or cash. There's an ATM inside.

No. Everything at 4th Street is bought in store or collected there. Catalyst operates no delivery service and ships nothing, anywhere in California.

There is. First purchase at Lancaster comes with 10% off.

Yes. The Catalyst Rewards Club adds points on everything you buy, which turn into member pricing and early event access. Free to join at the 4th Street counter or online.

ID showing you're 21 or over, plus debit or cash. If you're 18 to 20 and buying medicinal, bring your physician's recommendation or your MMIC.

The 4th Street shelves carry Astronauts, Coastal Sun, Smoken Promises, Cizi, California Love, On format: a standalone cartridge needs a compatible battery you already own, while an All-in-One arrives charged with one built in. Plugplay, Halfpipe, Blem, Wvy, Drops, Wyld, Punch Edibles, Whoa, Papa & Barkley, and Buddies, alongside our own Cat 4 line.

Catalyst's own pesticide panel, broader than California's required one, built after chemicals showed up in products that had already passed California-required compliance testing. Brands submit voluntarily, anything passing carries a Cat 4 sticker in store, and failures come off the wall regardless of how well they sold.

We stock them on both shelves, high-CBD and low-THC, for adults 21+ after the format rather than the intoxication.

Yes. Put it together on the online menu and pick it up at the 4th Street counter with ID.

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